冷激光血管再形成用于外周动脉治疗(CLiRpath)是由Spectranetics公司(Colorado Springs, CO, USA)开发的，使用该公司CVX-300 受激准分子激光发射308纳米波长“冷” 紫外光，通过纤维-光学发射设备和导管系统来控制能量脉冲，该导管系统由微小的、柔软的硅纤维制造的，每根直径只相当于一根头发。

　　这种激光能够精确瞄准并使得阻塞物气化，从而恢复血流，并且不会损伤周围的动脉。在激光治疗之后，在所有患者进行气囊血管重建术，帮助扩张曾经被阻塞的动脉。手术能够促进伤口愈合，确保患者在术后第一天即可出院。CLiRpath已经经过了严格的临床试验，在95％的患者保留了肢体并存活至6个月。

　　Cool Laser Saves Limbs from Amputation 

　　A painless laser procedure that requires no surgery and minimal recovery time can save limbs with blocked blood flow from amputation.

　　Cool laser revascularization for peripheral artery therapy (CLiRpath), developed by Spectranetics (Colorado Springs, CO, USA), uses the company’s CVX-300 excimer laser to deliver 308 nanometer wavelength “cool” ultraviolet light in short, controlled energy pulses via fiber-optic delivery devices and a catheter system made of tiny, flexible silica fibers, each about the width of a human hair.

　　The laser is able to precisely target and vaporize blockages, restoring blood flow without damage to the surrounding artery. After the laser procedure, balloon angioplasty is performed on almost all patients to help open the once-blocked artery. The surgery promotes wound healing, often enabling patients to leave the hospital the next day. CLiRpath has been the subject of rigorous clinical trials, with limb salvage observed in 95% of patients surviving to six months.